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FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia
《医学前沿(英文)》 2007年 第1卷 第2期 页码 185-191 doi: 10.1007/s11684-007-0035-1
关键词: endothelial phenomenon ectodermal Flk1CD34 postembryonic irradiated non-obese
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
《医学前沿(英文)》 2021年 第15卷 第4期 页码 608-620 doi: 10.1007/s11684-021-0836-7
关键词: t(8 21)(q22 q22) AML CD34+CD117dim/ CD34+CD117bri cell population gene expression prognosis
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches
null
《医学前沿(英文)》 2012年 第6卷 第3期 页码 248-262 doi: 10.1007/s11684-012-0206-6
The AML1-ETO fusion transcription factor is generated by the t(8;21) translocation, which is present in approximately 4%–12% of adult and 12%–30% of pediatric acute myeloid leukemia (AML) patients. Both human and mouse models of AML have demonstrated that AML1-ETO is insufficient for leukemogenesis in the absence of secondary events. In this review, we discuss the pathogenetic insights that have been gained from identifying the various events that can cooperate with AML1-ETO to induce AML in vivo. We also discuss potential therapeutic strategies for t(8;21) positive AML that involve targeting the fusion protein itself, the proteins that bind to it, or the genes that it regulates. Recently published studies suggest that a targeted therapy for t(8;21) positive AML is feasible and may be coming sometime soon.
关键词: AML1-ETO mouse model leukemia t(8 21) pathway hits mutation hematopoiesis Kasumi-1 CD34+
Immunohistochemical characterization of hepatic stem cell-related cells in developing human liver
XU Jun, HU Yong, WANG Jian, ZHANG Taiping, ZHOU Ji, YU Hongyu
《医学前沿(英文)》 2007年 第1卷 第3期 页码 264-268 doi: 10.1007/s11684-007-0050-2
关键词: origin Little mesenchymal tissue cords/mesenchymal tissue CD34
《医学前沿(英文)》 2022年 第16卷 第1期 页码 139-149 doi: 10.1007/s11684-021-0835-8
关键词: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Activation of phagocytosis by immune checkpoint blockade
null
《医学前沿(英文)》 2018年 第12卷 第4期 页码 473-480 doi: 10.1007/s11684-018-0657-5
Inhibition of macrophage-mediated phagocytosis has emerged as an essential mechanism for tumor immune evasion. One mechanism inhibiting the innate response is the presence of the macrophage inhibitory molecule, signal regulatory protein-α (SIRPα), on tumor-associated macrophages (TAMs) and its cognate ligand cluster of differentiation 47 (CD47) on tumor cells in the tumor microenvironment. On the basis of a recently discovered programmed death protein 1 (PD-1) in TAMs, we discuss the potential inhibitory receptors that possess new functions beyond T cell exhaustion in this review. As more and more immune receptors are found to be expressed on TAMs, the corresponding therapies may also stimulate macrophages for phagocytosis and thereby provide extra anti-tumor benefits in cancer therapy. Therefore, identification of biomarkers and combinatorial therapeutic strategies, have the potential to improve the efficacy and safety profiles of current immunotherapies.
关键词: CD47 PD-1 PD-L1 immunotherapy TAM phagocytosis macrophage
Kinetic study of the methanol to olefin process on a SAPO-34 catalyst
Mehdi SEDIGHI,Kamyar KEYVANLOO
《化学科学与工程前沿(英文)》 2014年 第8卷 第3期 页码 306-311 doi: 10.1007/s11705-014-1440-z
关键词: methanol to olefin SAPO-34 kinetic modeling elementary step
LI Jianxiong, LIU Zilong, DUAN Yonggang, YU Jing, ZHU Changhong, LI Shuang, XIE Changsheng
《医学前沿(英文)》 2007年 第1卷 第4期 页码 401-404 doi: 10.1007/s11684-007-0078-3
关键词: significant difference female endometrial angiogenesis nano-Cu/LDPE CD34
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
《环境科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 226-238 doi: 10.1007/s11783-013-0582-4
关键词:
cadmium (Cd)
low-Cd cultivar
pakchoi (
Autophagy and the nutritional signaling pathway
Long HE,Shabnam ESLAMFAM,Xi MA,Defa LI
《农业科学与工程前沿(英文)》 2016年 第3卷 第3期 页码 222-230 doi: 10.15302/J-FASE-2016106
关键词: Autophagy ULK1 complex VPS34 complex AMPK mTOR nutrient signaling
2008—2017年河南省腹泻患者来源单相鼠伤寒沙门菌ST34的基因组流行病学特征研究 Article
穆玉娇, 李瑞超, 杜鹏程, 张沛, 李岩, 崔生辉, Séamus Fanning, 白莉
《工程(英文)》 2022年 第15卷 第8期 页码 34-44 doi: 10.1016/j.eng.2022.05.006
Chen Wang, Jun Wang, Jianqiang Wang, Meiqing Shen
《环境科学与工程前沿(英文)》 2021年 第15卷 第2期 doi: 10.1007/s11783-020-1322-1
关键词: Selective catalytic reduction Cu/SAPO-34 catalyst Ion-exchanged K Low-temperature hydrothermal stability Fe/Beta catalyst
《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1687-z
● Organic solvent extracted fewer Cd/Pb in rapeseed oil than physical pressing.
关键词: Rapeseed oil Oil extraction technologies Human health risk assessment Cd/Pb-contaminated farmland Substitute planting
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 108-112 doi: 10.1007/s11684-009-0015-8
关键词: celecoxib CD437 melanoma A375 cell apoptosis cycle arrest
Ignacio Jorge Castellanos-Beltran, Gnouyaro Palla Assima, Jean-Michel Lavoie
《化学科学与工程前沿(英文)》 2018年 第12卷 第2期 页码 226-238 doi: 10.1007/s11705-018-1709-8
标题 作者 时间 类型 操作
Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow, heart, liver, muscle, lung, derma, kidney, and fat
FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia
期刊论文
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
期刊论文
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches
null
期刊论文
Immunohistochemical characterization of hepatic stem cell-related cells in developing human liver
XU Jun, HU Yong, WANG Jian, ZHANG Taiping, ZHOU Ji, YU Hongyu
期刊论文
Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific
期刊论文
Kinetic study of the methanol to olefin process on a SAPO-34 catalyst
Mehdi SEDIGHI,Kamyar KEYVANLOO
期刊论文
Correlative investigation of copper/low-density polyethylene nanocomposite on the endometrial angiogenesis in rats
LI Jianxiong, LIU Zilong, DUAN Yonggang, YU Jing, ZHU Changhong, LI Shuang, XIE Changsheng
期刊论文
Comparisons in subcellular and biochemical behaviors of cadmium between low-Cd and high-Cd accumulation
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
期刊论文
Promotional effect of ion-exchanged K on the low-temperature hydrothermal stability of Cu/SAPO-34 and
Chen Wang, Jun Wang, Jianqiang Wang, Meiqing Shen
期刊论文
Cultivars and oil extraction techniques affect Cd/Pb contents and health risks in oil of rapeseed grownon Cd/Pb-contaminated farmland
期刊论文
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
期刊论文